Cardiovascular Risk in Type 2 Diabetes Mellitus

by Nicolae Hancu

Publisher: Springer

Written in English
Cover of: Cardiovascular Risk in Type 2 Diabetes Mellitus | Nicolae Hancu
Published: Pages: 292 Downloads: 67
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Subjects:

  • Cardiovascular medicine,
  • Diabetes,
  • Pharmacology,
  • Diseases,
  • Cardiovascular Diseases,
  • Medical / Nursing,
  • Non-insulin-dependent diabetes,
  • Medical,
  • Endocrinology & Metabolism,
  • Cardiology,
  • Medical / Cardiology,
  • Cardiovascular system,
  • Complications,
  • Diabetic angiopathies
The Physical Object
FormatHardcover
Number of Pages292
ID Numbers
Open LibraryOL9057808M
ISBN 103540438033
ISBN 109783540438038

  Cardiovascular disease (CVD) is the leading cause of death and morbidity in people with diabetes. In , the total cost of diagnosed diabetes in the United States was $ billion (), and CVD is the largest contributor to the direct and indirect costs of diabetes (2,3).Diabetes is a well-established risk factor for CVD; in a retrospective study of nearly million individuals with type 2 Author: Robert H. Eckel, Azeez Farooki, Robert R. Henry, Gary G. Koch, Lawrence A. Leiter. Cardiovascular disease (CVD) is the leading cause of death in patients with diabetes mellitus, 1 but not all patients with diabetes have the same risk of developing CVD. CV risk increases with diabetes duration and is affected by other comorbidities like hypertension, dyslipidemia, metabolic syndrome, and chronic kidney disease. 2 Diabetic patients with existing CVD. In this book we reviewed insulin secretion in both healthy individuals and in patients with type 2 diabetes. Because of the risk associated with progression from insulin resistance to diabetes and cardiovascular complications increases along a continuum, we included several chapters on the damage of endothelial cells in type 2 diabetes . Individuals with type 2 diabetes mellitus have increased cardiovascular disease risk compared with those without diabetes. Treatment of the residual risk, other than blood pressure and LDL-cholesterol control, remains important as the rate of diabetes increases worldwide. The accelerated atherosclerosis and cardiovascular disease in diabetes Cited by:

  Cardiovascular disease (CVD) is a common comorbidity in type 2 diabetes (T2DM). CVD’s prevalence has been growing over time. To estimate the current prevalence of CVD among Cited by:   Four-fifths of patients with diabetes die of cardiovascular complications 4 and life expectancy is reduced by up to 10 years compared with that in persons without diabetes. 5 The risk Author: Linda Mellbin, Klas Malmberg. Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies Theodore Mazzone, Alan Chait, Jorge Plutzky Individuals with type 2 diabetes mellitus have increased cardiovascular disease risk compared with those without diabetes. Treatment of the residual risk. The common conditions coexisting with type 2 diabetes (e.g., hypertension and dyslipidemia) are clear risk factors for ASCVD, and diabetes itself confers independent risk. Numerous studies have shown the efficacy of controlling individual cardiovascular risk factors in preventing or slowing ASCVD in people with diabetes.

Cardiovascular Risk in Type 2 Diabetes Mellitus by Nicolae Hancu Download PDF EPUB FB2

Professor Hancu's major interest is related to clinical lipidology, visceral obesity, and cardiovascular risk in type 2 diabetes. He has published over papers and 14 books in this area. He has been invited. Professor Hancu's major interest is related to clinical lipidology, visceral obesity, and cardiovascular risk in type 2 diabetes.

He has published over papers and 14 books in this area. He has been invited as Visiting Professor at many universities in Madrid, Valladolid, Barcelona, and Los Angeles. Cardiovascular risk in diabetes mellitus Cardiovascular risks Diabetes Diabetes mellitus Heart conditions and diabetes Introduction The transition of care from the emergency department (ED) to Author: Charles V.

Pollack, William T. Ford, Gregory Volturo, Sameer Badlani, David J. Yu, Gerard X. Brogan. Type 2 diabetes mellitus (T2DM) is a recognized risk factor for cardiovascular (CV) disease (CVD).1 In a large, prospective, cohort study of individuals ≥30 yea We use cookies to enhance your experience on our continuing to use our website, you are agreeing to our use of cookies.

You can change your cookie settings Cited by: 5. Individuals with type Cardiovascular Risk in Type 2 Diabetes Mellitus book diabetes mellitus have increased cardiovascular disease risk compared with those without diabetes. Treatment of the residual risk, other than blood pressure and LDL-cholesterol control, remains important as the rate of diabetes Cited by: Patients with type 2 diabetes mellitus (T2DM) have two to four times increased cardiovascular disease (CVD) risk as compared to the general population – with CVD accounting for two out of every three deaths in patients with diabetes.

1 Despite significant progress in treatment during last four decades, patients with diabetes remain at high risk of cardiovascular morbidity. Cardiovascular Disease Risk Factors, Type 2 Diabetes Mellitus, and the Framingham Heart Study Caroline S.

Fox Corresponding Author: Caroline S. Fox MD MPH, Framingham Heart Study, National Heart, Lung, and Blood Institute, Division of Endocrinology, Metabolism, and Diabetes, 73 Mt Wayte Ave Suite #2 Cited by:   Diabetes mellitus (DM) is a metabolic disorder principally characterized by elevated blood glucose levels and by microvascular and macrovascular complications that considerably increase the morbidity and mortality related to the disease (1,2).Type I DM (insulin-dependent diabetes mellitus, IDDM) is characterized by a near-total reliance on exogenous insulin for survival, and long-standing type Cited by: Major modifiable cardiovascular risk factors in type 2 diabetes include smoking, dyslipidaemia, hypertension and, potentially, hyperglycaemia.

Numerous large randomized trials have investigated the effect of agents that lower serum cholesterol, blood pressure or plasma glucose Author: David Preiss, Naveed Sattar. Hyperglycemia is the major risk factor for microvascular complications in patients with type 2 diabetes (T2D).

However, cardiovascular disease (CVD) is the principal cause of death, and lowering HbA1c has only a modest effect on reducing CVD risk Cited by: 1.

Introduction. Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases with a worldwide prevalence of about % among the past decades, its prevalence has been on the rise and is estimated to increase to % until the year Diabetes and elevated plasma glucose are directly associated with all-cause and cardiovascular Author: Kui Zhang, Wenxing Yang, Hao Dai, Zhenhua Deng.

Abstract: Patients with diabetes mellitus have >2 the risk for developing heart failure (HF; HF with reduced ejection × fraction and HF with preserved ejection fraction). Cardiovascular outcomes, hospitalization, and prognosis are worse for patients with diabetes mellitus.

Type 2 Diabetes Mellitus and Heart Failure: A Scientific Statement From the American Heart Association and the Heart Failure Society of America.

Circulation ;Jun 6:[Epub ahead of print]. The following are key points to remember about this Scientific Statement from the American Heart Association and Heart Failure Society of America on type 2. Major modifiable cardiovascular risk factors in type 2 diabetes include smoking, dyslipidaemia, hypertension and, potentially, hyperglycaemia.

Consequently, there have been numerous large randomized trials investigating the effect on cardiovascular Author: David Preiss, Naveed Sattar. Cardiovascular disease (CVD) is the leading cause of death in people with diabetes mellitus.

1,2 Four large meta-analyses showed that after developing diabetes mellitus, the increase in the risk for fatal coronary heart Cited by: 1. Type 2 diabetes mellitus doubles the risk of major cardiovascular complications in patients with and in patients without established cardiovascular disease, such that the majority of patients Cited by: Laakso -- Atherogenesis in Diabetes \/ D.

Dabelea -- Hyperglycaemia as Cardiovascular Risk in Type 2 Diabetes \/ P. Brunetti, G. Perriello -- Glidazide and Diabetic Angiopathy \/ A.J. Weekes -- Clinical Experience with Repaglinide, the First Prandial Glucose Regulator in Type 2 Diabetes.

diagnostics Review Current Data Regarding the Relationship between Type 2 Diabetes Mellitus and Cardiovascular Risk Factors Cosmin Mihai Vesa 1, Loredana Popa 2, Amorin Remus Popa 2,3, Marius Rus 2.

In contrast, two other recent large-scale clinical trials of intensive glucose lowering (achieved HbA 1c range –%) in patients with type 2 diabetes (the Action to Control Cardiovascular Risk in Diabetes [ACCORD] and VA Trial of Glycemic Control and Complications in Diabetes Mellitus Type 2 Author: Sophia Zoungas, John Chalmers, Anushka Patel.

The authors concluded that among participants with type 2 diabetes mellitus in the Look AHEAD trial, the ILI did not appear to modify the risk of HF. Higher baseline CRF and sustained improvements in CRF and weight loss were associated with lower risk.

Type 2 diabetes mellitus is associated with an increased risk of cardiovascular disease and mortality[1, 2].Cardiovascular events account for approximately 70% of deaths in older patients with type 2 diabetes mellitus[].Furthermore, short- and long-term survival following a myocardial infarction is lower in patients with type 2 diabetes mellitus Cited by:   Leiter LA, Cariou B, Muller-Wieland D, et al.

Efficacy and safety of alirocumab in insulin-treated individuals with type 1 or type 2 diabetes and high cardiovascular risk: the ODYSSEY DM-INSULIN randomized by: 4. A recently published analysis in Hypertension suggests that thiazide use, versus nonuse, is associated with excess risk of adverse cardiovascular outcomes in patients with diabetes mellitus enrolled in the ACCORD trial (Action to Control Cardiovascular Risk in Diabetes Author: Steven M.

Smith, Almut G. Winterstein, Carl J. Pepine, Rhonda M. Cooper-DeHoff. Type 2 diabetes mellitus (T2DM) is commonly accompanied by other cardiovascular disease (CVD) risk factors, such as hypertension, obesity, and dyslipidemia. Furthermore, CVD is the Cited by:   "It is intriguing that [major adverse cardiovascular event (MACE)] risk is similar in men and women with diabetes mellitus, even though women were less well treated in terms of their other risk factors, and that prior studies reported women had about 25% to 50% higher risk of CVD.

Commonly cardiovascular risk (CVR) is linked to type 2 diabetes mellitus as this type is known to be part of the metabolic syndrome, which includes other cardiovascular factors such as hypertension, dyslipidemia. Inversely, CVR of type 1 diabetes mellitus (T1DM) is currently being debated apart from the occurrence of diabetic nephropathy Cited by: 8.

database diabetes mellitus, type 2 primary health care risk factors Sources of Funding, see page BACKGROUND: With recent changes in the United Kingdom’s clinical practice for diabetes mellitus care, contemporary estimates of sex disparities in cardiovascular risk and risk Cited by: 5. The draft guidance will replace the FDA guidances for industry, “Diabetes Mellitus – Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes,” published in.

Aspirin therapy ( mg/day) may be considered as a primary prevention strategy in those with type 1 or type 2 diabetes who are at increased CV risk. This includes most men and women with diabetes aged ≥50 years who have at least one additional major risk. Coronary heart disease (CHD) and stroke, collectively cardiovascular disease (CVD), are caused by narrowing and blockage of the arteries supplying the heart and brain, respectively.

In type 2 diabetes. One of the paradoxes in the studies of cardiovascular complications in type 2 diabetes is that at diagnosis individuals with type 2 diabetes already have substantially increased prevalence of CHD and stroke ().Although a part of this risk could be attributed to asymptomatic hyperglycemia, fulfilling the criteria for diabetes Cited by: Patients with type 2 diabetes have risks of death and cardiovascular events that are 2 to 4 times as great as the risks in the general population.

1 Results from randomized trials support a range Cited by: Patients with type 2 diabetes who had five risk-factor variables within the target ranges appeared to have little or no excess risk of death, myocardial infarction, or stroke, as compared with the.